崔效源,男,1993年8月生,山西寿阳人,理学博士,讲师。2015年本科毕业于沈阳药科大学制药工程专业,2018年硕士毕业于沈阳药科大学有机化学专业,2023年博士毕业于华东师范大学物理化学专业,2023年9月入职晋中学院化学化工系。主要从事过渡金属催化以及含硫类生物活性分子的构建。迄今在包括ACS Catal.、Nat. Commun.、Org. Lett.、Org. Chem. Front.等权威期刊发表SCI学术论文数篇。参与国家自然科学基金三项面上项目3项。
主要科研成果:
[1] X.-Y. Cui, Z.-T. Ye, F. Zhou, C.-G. Ji, H.-H. Wu, J. Zhou, Au(I)-Catalyzed Formal Intermolecular Carbene Insertion into Vinylic C(sp2)-H Bonds and Allylic C(sp3)-H Bonds. ACS Catal. 2023, 13, 1554-1561. (IF=12.9,中科院一区)
[2] X.-Y. Cui, F. Zhou, J, Zhou, Asymmetric Tandem Reactions Achieved by Chiral Amine & Gold(I) Cooperative Catalysis. Chin. J. Org. Chem. 2022, 42, 3033-3050.
[3] X.-Y. Cui, Y.-L. Zhao, Y.-M. Chen, S.-Z. Dong, F. Zhou, H.-H. Wu, J. Zhou, Au-Catalyzed Formal Allylation of Diazo(thio)oxindoles: Application to Tandem Asymmetric Synthesis of Quaternary Stereocenters. Org. Lett. 2021, 23, 4864-4869. (IF=5.2,中科院一区)
[4] B.-S. Mu, X.-Y. Cui, X.-P. Zeng, J.-S. Yu, J. Zhou, Modular synthesis of chiral 1,2-dihydropyridines via Mannich/Wittig/cycloisomerization sequence that internally reuses waste. Nat. Commun. 2021, 12, 2219. (IF=16.6,中科院一区)
[5] P.-W. Xu, X.-Y. Cui, C. Chen, F. Zhou, J.-S. Yu, Y.-F. Ao, J, Zhou, Enantioselective Synthesis of Cα‑Tetrasubstituted N‑Hydroxyl-α-amino Nitriles via Cyanation of Ketonitrones Using Me2(CH2Cl)SiCN. Org. Lett. 2021, 23, 8471-8476. (IF=5.2,中科院一区)
[6] S.-L. Xie, X.-Y. Cui, X.-T. Gao, F. Zhou, H.-H. Wu, J. Zhou, Stereoselective defluorinative carboxylation of gem-difluoroalkenes with carbon dioxide. Org. Chem. Front. 2019, 6, 3678-3682. (IF=5.4,中科院一区)
[7] 崔效源,张美慧,高河勇,刘振德,董金华,尼拉帕尼的合成工艺改进. 中国药物化学杂志. 2018, 28 (06).
[8] 周剑,穆博帅,崔效源,余金生,一类手性1,2-二氢吡啶类化合物及其制备方法和应用(申请号:201910655772.1)